The central nervous system (CNS) in most vertebrates forms initially as a flat sheet of cells, which subsequently rolls up and fuses shut to form the hollow neural tube, which is the precursor to the CNS. The enriched apical actin in the closing neural tube (shown in green in the image) is central to cell shape changes that contribute to the rolling up process.
Image: Color micrograph showing a cross-sectional (transverse) view of the closing neural tube in a Xenopus embryo. Actin is shown in green.
Menstruation products* but yeah real safety would be making them free as they should be 🙃
Microbiologists have learned how a probiotic bacterium used to treat irritable bowel syndrome can soothe gut bacterial infections caused by salmonella, paving the way for potential relief from foodborne illnesses that affect millions of people annually.
Sofia Ionescu (1920-2008) was a Romanian neurosurgeon, thought to be one of the first female neurosurgeons in the world.
She studied medicine in Bucharest, and in 1943 became part of the first team of Romanian neurosurgeons. She continued practicing the profession for almost five decades and received numerous awards for her lifesaving work.
Urine sediment from a 6 year-old, male-intact, Rottweiler. The patient has a multi-year history of recurrent urinary tract infections. He recently presented to his primary care veterinarian for being unable to urinate. Radiographs showed no bladder stones, but a penile ultrasound showed many obstructing the urethra. The dog was then referred for surgery to relieve the obstruction…
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The surgeons were kind enough to snag us some urine! The urine was full of these hexagonal crystals….consistent with cystine crystals! Yes, the amino acid cystine. In addition, there were all shapes of sperms (see them swimming in the background!) along with many inflammatory cells and some bacteria.
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Diagnosis: Cystine crystalluria. This is a very rare occurrence in veterinary medicine! Such patient’s often have a genetic defect in the metabolism or transport of cystine, allowing the amino acid to accumulate in blood. Once it filters into urine, cystine will polymerize into crystals and sometimes form stones. Cystine stones do not obstruct x-rays…hence they cannot be found on standard radiographs (termed radiolucent). The patient is recovering well following surgery, and may require a special diet to help with his disease.
Went out to a vernal pool today and saw some crazy toad action
Connective tissue
Anne Weston, London Research Institute, Cancer Research UK
This false-coloured scanning electron micrograph shows connective tissue removed from a human knee during arthroscopic surgery. Individual fibres of collagen can be distinguished and have been highlighted by the creator using a variety of colours. The horizontal field width of the image is 16 microns.
Hematopoietic stem cells ready for re-injection. Image from Steve Gschmeisserner.
Usual interstitial pneumonia
It has the loose fibroblastic balls (pink balls) next to relatively normal lung parenchyma (thin septae) and a bronchiole (the blueish wrinkly thing)
(Via pulmonary pathology)
Medical lung is like… impossible. COP. DAD. DIP. NSIP. BOOP. POOP. SCHMOOP. No idea. It all looks the same to me.
Right lateral thoracic wall mass from a 10 year-old, female-spayed, Golden Retriever. Approximately six months ago the owner noticed a small, firm swelling on the patient’s right chest. No doubt it grew with time, as it finally got large enough for the owner to become truly concerned! The patient is clinically healthy otherwise.
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The most prominent feature on the cytology were these gorgeous globules of magenta, streaming material! In fact, the entire slide was imbued with this color when you looked at it without a microscope. The substance is most likely matrix produced by cancer cells. Matrix of this color is commonly observed in chrondrosarcomas. Occasional malignant spindle-shaped cells were found imbedded in the matrix.
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Diagnosis: Chondrosarcoma. Well , that’s the most likely diagnosis given the location and appearance of the neoplastic cells and matrix! Other possibilities include a myxosarcoma (which produces a mucous like material!) or osteosarcoma (malignant primary bone tumor). Chondrosarcomas are often regionally invasive but rarely metastasize. If the owner is on board with a chest wall resection, the patient will have a good prognosis :-)
An assortment of scientific things from the wonderful world of biology
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